Anticancer agent 216

• Description:

  Anticancer agent 216 (34A) is a Camptothecin compound, with IC50 values of 9.6 nM and 11.6 nM in MCF-7 cells and MDA-MB-231 cells, respectively[1].

• UNSPSC:

  12352005

• Target:

  Topoisomerase

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/anticancer-agent-216.html

• Smiles:

  C[C@@H](C1=C2C(C(N3C2)=CC([C@](O)(C(OC4)=O)CC)=C4C3=O)=NC5=CC(OCO6)=C6C=C51)N

• Molecular Formula:

  C23H21N3O6

• Molecular Weight:

  435.43

• References & Citations:

  [1]Furao Zhang, et al. Camptothecin compound, preparation method therefor and use thereof. Patent. WO2023030364.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2916406-02-3]