Antitumor agent-48

• UNSPSC Description:

  Antitumor agent-48 (Compound 4a) is a 2,3-dehydrosilybin derivative with an antitumor activity. Antitumor agent-48 shows cytotoxic activity against MCF-7, NCI-H1299, HepG2 and HT29 cells with IC50 values of 8.06 µM, 13.1 µM, 16.51 µM and 12.44 µM, respectively[1].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/antitumor-agent-48.html

• Solubility:

  10 mM in DMSO

• Smiles:

  COC1=CC(C2OC3=C(OC2CO)C=CC(C4=C(C(C5=C(C=C(C=C5O4)OC(N6CCOCC6)=O)O)=O)OC(N7CCOCC7)=O)=C3)=CC=C1O

• Molecular Weight:

  706.65

• References & Citations:

  [1]Qiuchan Wu, et al. Synthesis and antitumor activity of novel silibinin and 2,3-dehydrosilybin derivatives with carbamate groups. Med Chem Res. 2022;31(4):533-544.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  9007-83-4