Antitumor agent-47

• Description:

  Antitumor agent-47 (Compound 3e) is a silibinin derivative with an antitumor activity. Antitumor agent-47 shows cytotoxic activity against NCI-H1299 and HT29 cells with IC50 values of 8.07 µM and 6.27 µM, respectively[1].

• UNSPSC:

  12352005

• Target:

  HSP

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage; Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/antitumor-agent-47.html

• Solubility:

  10 mM in DMSO

• Smiles:

  COC1=CC(C2OC3=C(OC2CO)C=CC(C4=C(C(C5=C(C=C(C=C5O4)OC(N6CCCC6)=O)O)=O)O)=C3)=CC=C1O

• Molecular Formula:

  C30H27NO11

• Molecular Weight:

  577.54

• References & Citations:

  [1]Qiuchan Wu, et al. Synthesis and antitumor activity of novel silibinin and 2,3-dehydrosilybin derivatives with carbamate groups. Med Chem Res. 2022;31 (4) :533-544.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2917547-24-9]