STAT3-IN-30

• Description:

  STAT3-IN-30 (compound 9c) is a STAT3 inhibitor with an EC50 of 13.8 μM[1].

• UNSPSC:

  12352005

• Target:

  STAT

• Type:

  Reference compound

• Related Pathways:

  JAK/STAT Signaling; Stem Cell/Wnt

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/stat3-in-30.html

• Smiles:

  O=C(O)C1=CC=C(N(CC2=CC=C(C3CCCCC3)C=C2)C(CN(CC4=C(F)C(F)=C(F)C(F)=C4F)S(=O)(C5=CC=C(C(F)(F)F)C=C5)=O)=O)C=C1O

• Molecular Formula:

  C36H30F8N2O6S

• Molecular Weight:

  770.69

• References & Citations:

  [1]Eiring AM, et al. Combined STAT3 and BCR-ABL1 inhibition induces synthetic lethality in therapy-resistant chronic myeloid leukemia. Leukemia. 2015 Mar;29 (3) :586-597. doi: 10.1038/leu.2014.245. Epub 2014 Aug 19. Erratum in: Leukemia. 2017 May;31 (5) :1253-1254.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1803281-30-2]