ATR-IN-4
CAT:
804-HY-145312-02
Size:
10 mM / 1 mL
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
ATR-IN-4
- CAS Number: 2574545-45-0
- UNSPSC Description: ATR-IN-4 is a potent ATR (Ataxia telangiectasia mutated gene Rad 3-associated kinase) inhibitor. ATR-IN-4 inhibits growth of human prostate cancer cells DU145 and human lung cancer cells NCI-H460 with IC50s of 130.9 nM and 41 .33 nM, respectively. (Patent CN112142744A, compound 13)[1].
- Target Antigen: ATM/ATR
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage;PI3K/Akt/mTOR
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/atr-in-4.html
- Solubility: DMSO : 25 mg/mL (ultrasonic)
- Smiles: CN1C(C2=CC(N3[C@@H](COCC3)C)=NN4C2=CN=C4C5=NNC=C5)=CC=N1
- Molecular Weight: 364.40
- References & Citations: [1]Substituted fused heteroaromatic bicyclic compounds as kinase inhibitors and uses thereof. CN112142744A.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported