ATR-IN-6

ATR-IN-6

• CAS Number: 2746446-99-9
• UNSPSC Description: ATR-IN-6 is a potent inhibitor of ATR. ATR is a class of protein kinases involved in genome stability and DNA damage repair, and is a member of the PIKK family. ATR-IN-6 has the potential for the research of ATR kinase-mediated diseases such as proliferative diseases and cancer (extracted from patent WO2021233376A1, compound A22)[1].
• Target Antigen: ATM/ATR
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;PI3K/Akt/mTOR
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/atr-in-6.html
• Solubility: 10 mM in DMSO
• Smiles: OCC1=CC(C2=NC(N3[C@@H](COCC3)C)=CC(C4=C(N(C5=CN=CC(F)=C5)N=C4C)C)=N2)=C6C(NC=C6)=C1
• Molecular Weight: 513.57
• References & Citations: [1]Zhao, Yanping, et al. 2,4,6-Trisubstituted pyrimidine compounds as atr kinase inhibitors. Patent WO2021233376A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported