ATR-IN-21

• UNSPSC Description:

  ATR-IN-21 (compound 60) is a potent ATR inhibitor with an IC50 value of [1].

• Target Antigen:

  ATM/ATR

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;PI3K/Akt/mTOR

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/atr-in-21.html

• Solubility:

  10 mM in DMSO

• Smiles:

  N#CC1(CCC(CC1)N)C2=CC(N3[C@@H](COCC3)C)=NC4=C2C=CN=C4C5=NNC=C5

• Molecular Weight:

  417.51

• References & Citations:

  [1]YuLi Xie, et al. Naphthyridine derivative as atr inhibitor and method for preparing same. WO2023016529A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2905312-17-4