ATR-IN-5

ATR-IN-5

• CAS Number: 2601571-19-9
• UNSPSC Description: ATR-IN-5 is a potent inhibitor of ATR. ATR is a class of protein kinases involved in genome stability and DNA damage repair, and is a member of the PIKK family. ATR-IN-5 has the potential for the research of ATR kinase-mediated diseases such as proliferative diseases and cancer (extracted from patent CN112047938A, compound D24)[1].
• Target Antigen: ATM/ATR
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;PI3K/Akt/mTOR
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/atr-in-5.html
• Solubility: 10 mM in DMSO
• Smiles: CNC1=NC2=CC=CC=C2N1C3=NC(N4[C@@H](COCC4)C)=CC(C5=C(N(C6CCNCC6)N=C5C)C(F)(F)F)=N3
• Molecular Weight: 555.60
• References & Citations: [1]Zhao, Yanping, et al. 2,4,6-Trisubstituted pyrimidine compounds as atr kinase inhibitors. Patent CN112047938A.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported