ATR-IN-30

ATR-IN-30

• CAS Number: 3010273-13-6
• UNSPSC Description: ATR-IN-30 is a selective ATR ligand, and can be used for synthesis of ATR PROTACs, such as PROTAC ATR degrader-2 (HY-161615)[1].
• Target Antigen: ATM/ATR
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;PI3K/Akt/mTOR
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/atr-in-30.html
• Smiles: O=C(C1=NC(C2=CC=C(C(N3CCN(C(OC(C)(C)C)=O)CC3)=O)C=C2)=CN=C1N)NC4=CC=CC=C4
• Molecular Weight: 502.56
• References & Citations: [1]Wang Y, et al. Discovery of Selective and Potent ATR Degrader for Exploration its Kinase-Independent Functions in Acute Myeloid Leukemia Cells. Angew Chem Int Ed Engl. 2024 Apr 22;63(17):e202318568.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported