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ATR-IN-9

CAT: 0804-HY-145450Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-145450Size:1 Each
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Description
ATR-IN-9 is a potent inhibitor of Ataxia-telangiectasia and RAD-3-related protein kinase (ATR) extracted from patent WO2020087170A1, compound 59, has an IC50 of 10 nM[1].
CAS Number
2417513-43-8
UNSPSC
12352005
Target
ATM/ATR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/atr-in-9.html
Solubility
10 mM in DMSO
Smiles
OC1(CCC(C)(CC1)C#N)C2=C3C(N(C4=NNC=C4)N=C3)=NC(N5[C@@H](COCC5)C)=C2
Molecular Formula
C22H27N7O2
Molecular Weight
421.50
References & Citations
[1]Crane SN, et, al. Compounds, pharmaceutical compositions, and methods of preparing compounds and of their use as atr kinase inhibitors. WO2020087170A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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