IK-175

CAT: 0804-HY-141609-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-141609-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IK-175 is a selective and orally active aryl hydrocarbon receptor (AHR) inhibitor. IK-175 effectively blocks AHR from translocating from the cytoplasm to the nucleus. IK-175 is highly selective for AHR over other receptors, transporters, and kinases[1].
CAS Number
[2247950-42-9]
Product Name Alternative
AHR antagonist 5 (free base)
UNSPSC
12352005
Target
Aryl Hydrocarbon Receptor
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ahr-antagonist-5-free-base.html
Purity
99.78
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C)C(C=N1)=C2N1C(N[C@H]3CC4=C(CC3)NC5=CC=CC=C45)=NC(C6=CN=CC(F)=C6)=N2
Molecular Formula
C25H24FN7
Molecular Weight
441.50
References & Citations
[1]Marta Sanchez-Martin, et al. Ahr inhibitors and uses thereof. WO2021142180A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1

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