IK-862

• Description :

  IK-862 is a selective inhibitor of TACE[1].

• UNSPSC :

  12352005

• Target :

  TNF Receptor

• Type :

  Reference compound

• Related Pathways :

  Apoptosis

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/ik-862.html

• Solubility :

  10 mM in DMSO

• Smiles :

  C[C@]1(C2=CC=C(C=C2)OCC3=CC(C)=NC4=C3C=CC=C4)C(N(CC1)[C@H](C)C(NO)=O)=O

• Molecular Formula :

  C25H27N3O4

• Molecular Weight :

  433.50

• References & Citations :

  [1]Georgiadis D, et al. Specific targeting of metzincin family members with small-molecule inhibitors: progress toward a multifarious challenge. Bioorg Med Chem. 2008;16 (19) :8781-8794. doi:10.1016/j.bmc.2008.08.058

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [478911-60-3]