CQ-ER

• UNSPSC Description:

  CQ-ER is a Coumarin (HY-N0709)-Quinazolinone based endoplasmic reticulum (ER)-targeted photosensitizer. CQ-ER can cause ferroptosis, thereby enhancing photodynamic therapy (PDT)[1].

• Target Antigen:

  Ferroptosis

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/cq-er.html

• Smiles:

  O=C(C(C1=NC2=CC=C(OCC3=CN(CCNS(C4=CC=C(C)C=C4)(=O)=O)N=N3)C=C2C(N1)=O)=C5)OC6=C5C=CC(N(CC)CC)=C6

• Molecular Weight:

  655.72

• References & Citations:

  [1]Xuzi Zhao, et al. Coumarin-Quinazolinone based photosensitizers: Mitochondria and endoplasmic reticulum targeting for enhanced phototherapy via different cell death pathways. Eur J Med Chem. 2024 Oct 19:280:116990.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported