ERα/ERβ antagonist-1

• UNSPSC Description:

  ERα/ERβ antagonist-1 (Compound 10) is partial antagonists of ERα and ERβ. ERα/ERβ antagonist-1 reduces ERα and ERβ activity in a dose-dependent manner in HepG2 liver cells[1].

• Target Antigen:

  Estrogen Receptor/ERR

• Type:

  Reference compound

• Related Pathways:

  Vitamin D Related/Nuclear Receptor

• Field of Research:

  Cancer; Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/erα-erβ-antagonist-1.html

• Smiles:

  OC1=C(CC=C)C=C(C2=C(OC(CCC)=O)C=CC(CC=C)=C2)C=C1

• Molecular Weight:

  336.42

• References & Citations:

  [1]Tinivella A, et al. Exploring Biological Targets of Magnolol and Honokiol and their Nature-Inspired Synthetic Derivatives: In Silico Identification and Experimental Validation of Estrogen Receptors. J Nat Prod. 2024 Nov 22;87(11):2568-2579.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2482778-93-6