ER-819762

• UNSPSC Description:

  ER-819762 is an orally active, highly selective prostaglandin E2 (PGE2) EP4 receptor antagonist with an EC50 of 70 nM against human EP4 receptor. ER-819762 can be used for rheumatoid arthritis research[1].

• Target Antigen:

  Prostaglandin Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/er-819762.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CCN1C2(CCN(CC2)CC3=CC(C)=CC(C)=C3)C(N(CC4=CC(OC)=C5)C1=O)=C[C@H](C)C4=C5OC

• Molecular Weight:

  489.65

• References & Citations:

  [1]Chen Q, et al. A novel antagonist of the prostaglandin E(2) EP(4) receptor inhibits Th1 differentiation and Th17 expansion and is orally active in arthritis models. Br J Pharmacol. 2010 May;160(2):292-310.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1155773-15-1