CQ-16

CAT: 0931-T201540-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T201540-01Size:10 mg
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CAS Number
3024354-59-1
Target
PSMA|||Epigenetic Reader Domain|||PARP|||PROTACs
Related Pathways
Chromatin/Epigenetic|||Immunology/Inflammation|||DNA Damage/DNA Repair|||PROTAC
Bioactivity
CQ-16 is an orally active small molecule drug conjugate (SMDC) that targets prostate-specific membrane antigen (PSMA) . It exhibits high selectivity in its antiproliferative activity between PSMA-positive and PSMA-negative prostate cells. Additionally, CQ-16 possesses PARP inhibitory activity (IC50=1 nM) .
Smiles
C(=O)(C1(NC(CCC(NCCCC[C@H](NC(N[C@@H](CCC(O)=O)C(O)=O)=O)C(O)=O)=O)=O)CC1)N2CCN(C(=O)C3=CC(CC=4C=5C(C(=O)NN4)=CC=CC5)=CC=C3F)CC2
Molecular Formula
C40H47FN8O12
Molecular Weight
850.85
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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