CQ-16

• Target:

  PSMA|||Epigenetic Reader Domain|||PARP|||PROTACs

• Related Pathways:

  Chromatin/Epigenetic|||Immunology/Inflammation|||DNA Damage/DNA Repair|||PROTAC

• Bioactivity:

  CQ-16 is an orally active small molecule drug conjugate (SMDC) that targets prostate-specific membrane antigen (PSMA) . It exhibits high selectivity in its antiproliferative activity between PSMA-positive and PSMA-negative prostate cells. Additionally, CQ-16 possesses PARP inhibitory activity (IC50=1 nM) .

• Smiles:

  C(=O)(C1(NC(CCC(NCCCC[C@H](NC(N[C@@H](CCC(O)=O)C(O)=O)=O)C(O)=O)=O)=O)CC1)N2CCN(C(=O)C3=CC(CC=4C=5C(C(=O)NN4)=CC=CC5)=CC=C3F)CC2

• Molecular Formula:

  C40H47FN8O12

• Molecular Weight:

  850.85

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3024354-59-1