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Antitumor agent-173

CAT: 0804-HY-161821Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-161821Size:1 Each
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Description
Antitumor agent-173 (Compound 4b) is a prodrug of Cycloicaritin. Antitumor agent-173 is a substrate for OATP2B1. Antitumor agent-173 selectively inhibits the growth of tumor Antitumor agent-173 significantly increases the oral bioavailability of Cycloicaritin and exerts good antitumor activity and safety[1].
CAS Number
9007-83-4
UNSPSC
12352005
Target
Interleukin Related; MMP; TNF Receptor
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antitumor-agent-173.html
Smiles
COC(C=C1)=CC=C1C2=C(OC(N[C@@H](CC(C)C)C(O)=O)=O)C(C3=C(O)C=C4C(CCC(C)(C)O4)=C3O2)=O
Molecular Formula
C28H31NO9
Molecular Weight
525.55
References & Citations
[1]Wang W, et al. Design, synthesis and evaluation of carbamate-bridged amino acid prodrugs of cycloicaritin with improved antitumor activity, aqueous solubility and phase II metabolic stability. Eur J Med Chem. 2024 Jul 2;276:116646.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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