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L-Ascorbic acid (GMP)

CAT: 0804-HY-B0166G-02Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0166G-02Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
L-Ascorbic acid (L-Ascorbate) (GMP) is Ascorbic acid produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. L-Ascorbic acid is an inhibitor of Cav 3.2 channels[1].
CAS Number
50-81-7
Product Name Alternative
L-Ascorbate (GMP) ; Vitamin C (GMP)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Calcium Channel; Endogenous Metabolite; Reactive Oxygen Species (ROS)
Type
GMP Small Molecules
Related Pathways
Apoptosis; Immunology/Inflammation; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer; Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/l-ascorbic-acid-gmp.html
Purity
99.2
Solubility
10 mM in DMSO
Smiles
OC([C@@]1([H])[C@H](CO)O)=C(O)C(O1)=O
Molecular Formula
C6H8O6
Molecular Weight
176.12
Precautions
H302, H315, H319, H335
References & Citations
[1]Barlian A, et al. Chondrogenic differentiation of Wharton's Jelly mesenchymal stem cells on silk spidroin-fibroin mix scaffold supplemented with L-ascorbic acid and platelet rich plasma. Sci Rep. 2020 Nov 10;10 (1) :19449.|[2]Mekala NK, et al. Enhanced proliferation and osteogenic differentiation of human umbilical cord blood stem cells by L-ascorbic acid, in vitro. Curr Stem Cell Res Ther. 2013 Mar;8 (2) :156-62.
Shipping Conditions
Blue Ice
Storage Conditions
Keep sealed, protected from light and store at room temperature
Scientific Category
GMP Small Molecules
Clinical Information
Phase 2

Chemical Information

L-Ascorbic Acid

L-ascorbic acid is the L-enantiomer of ascorbic acid and conjugate acid of L-ascorbate. It has a role as a geroprotector, a coenzyme, a cofactor, a flour treatment agent, a plant metabolite, a food antioxidant, a food colour retention agent and a skin lightening agent. It is a vitamin C and an ascorbic acid. It is a conjugate acid of a L-ascorbate. It is an enantiomer of a D-ascorbic acid.

CAS Number50-81-7
PubChem CID54670067
IUPAC Name(2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one
Molecular FormulaC6H8O6
Molecular Weight176.12
XLogP-1.6
Topological Polar Surface Area107
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count6
Rotatable Bond Count2
Heavy Atom Count12
Formal Charge0
Complexity232
SMILES
C([C@@H]([C@@H]1C(=C(C(=O)O1)O)O)O)O
InChI
InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1
InChIKey
CIWBSHSKHKDKBQ-JLAZNSOCSA-N
Chemical Structure
2D Structure
2D structure of L-Ascorbic Acid
CAS: 50-81-7
CID: 54670067
Formula: C6H8O6
MW: 176.12
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight176.12
XLogP3-1.6
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count6
Rotatable Bond Count2
Exact Mass176.03208797
Monoisotopic Mass176.03208797
Topological Polar Surface Area107 Ų
Heavy Atom Count12
Formal Charge0
Complexity232
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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