L-Ascorbic acid (GMP)

• Description:

  L-Ascorbic acid (L-Ascorbate) (GMP) is Ascorbic acid (HY-B0166) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. L-Ascorbic acid is an inhibitor of Cav 3.2 channels[1].

• Product Name Alternative:

  L-Ascorbate (GMP) ; Vitamin C (GMP)

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Apoptosis; Calcium Channel; Endogenous Metabolite; Reactive Oxygen Species (ROS)

• Type:

  GMP Small Molecules

• Related Pathways:

  Apoptosis; Immunology/Inflammation; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Cancer; Metabolic Disease; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/l-ascorbic-acid-gmp.html

• Purity:

  99.2

• Solubility:

  10 mM in DMSO

• Smiles:

  OC ([C@@]1 ([H]) [C@H] (CO) O) =C (O) C (O1) =O

• Molecular Formula:

  C6H8O6

• Molecular Weight:

  176.12

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Barlian A, et al. Chondrogenic differentiation of Wharton's Jelly mesenchymal stem cells on silk spidroin-fibroin mix scaffold supplemented with L-ascorbic acid and platelet rich plasma. Sci Rep. 2020 Nov 10;10 (1) :19449.|[2]Mekala NK, et al. Enhanced proliferation and osteogenic differentiation of human umbilical cord blood stem cells by L-ascorbic acid, in vitro. Curr Stem Cell Res Ther. 2013 Mar;8 (2) :156-62.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Keep sealed, protected from light and store at room temperature

• Scientific Category:

  GMP Small Molecules

• Clinical Information:

  Phase 2

• CAS Number:

  50-81-7