L-Ascorbic acid (GMP)

• UNSPSC Description:

  L-Ascorbic acid (L-Ascorbate) (GMP) is L-Ascorbic acid (HY-B0166) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. L-Ascorbic acid is an inhibitor of Cav 3.2 channels[1].

• Target Antigen:

  Apoptosis; Calcium Channel; Endogenous Metabolite; Reactive Oxygen Species

• Type:

  GMP Small Molecules

• Related Pathways:

  Apoptosis;Immunology/Inflammation;Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling;NF-κB

• Field of Research:

  Cancer; Metabolic Disease; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/l-ascorbic-acid-gmp.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC([C@@]1([H])[C@H](CO)O)=C(O)C(O1)=O

• Molecular Weight:

  176.12

• References & Citations:

  [1]Barlian A, et al. Chondrogenic differentiation of Wharton's Jelly mesenchymal stem cells on silk spidroin-fibroin mix scaffold supplemented with L-ascorbic acid and platelet rich plasma. Sci Rep. 2020 Nov 10;10(1):19449.|[2]Mekala NK, et al. Enhanced proliferation and osteogenic differentiation of human umbilical cord blood stem cells by L-ascorbic acid, in vitro. Curr Stem Cell Res Ther. 2013 Mar;8(2):156-62.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Clinical Information:

  Phase 2

• CAS Number:

  50-81-7