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L-Ascorbic acid 2-phosphate (trisodium)

CAT: 0804-HY-107837-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-107837-01Size:500 mg
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Description
L-Ascorbic acid 2-phosphate trisodium (2-Phospho-L-ascorbic acid trisodium) is a long-acting vitamin C derivative that can stimulate collagen formation and expression[1]. L-Ascorbic acid 2-phosphate trisodium (2-Phospho-L-ascorbic acid trisodium) can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs) . L-Ascorbic acid 2-phosphate trisodium (2-Phospho-L-ascorbic acid trisodium) increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation[2][3].
CAS Number
66170-10-3
Product Name Alternative
2-Phospho-L-ascorbic acid (trisodium)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite; Phosphatase; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/l-ascorbic-acid-2-phosphate-trisodium.html
Purity
98.60
Solubility
H2O : 150 mg/mL (ultrasonic)
Smiles
O[C@@H](CO)[C@@H](O1)C(O[Na])=C(OP(O[Na])(O[Na])=O)C1=O
Molecular Formula
C6H6Na3O9P
Molecular Weight
322.05
Precautions
H302, H315, H319, H335
References & Citations
[1]Shima N, et al. Increased proliferation and replicative lifespan of isolated human corneal endothelial cells with L-ascorbic acid 2-phosphate.Invest Ophthalmol Vis Sci. 2011 Nov 7;52 (12) :8711-7.|[2]Kurata S, et al. Epidermal growth factor inhibits transcription of type I collagen genes and production of type I collagen in cultured human skin fibroblasts in the presence and absence of L-ascorbic acid 2-phosphate, a long-acting vitamin C derivative.J Biol Chem. 1991 May 25;266 (15) :9997-10003.|[3]Kyllönen L, et al. Effects of different serum conditions on osteogenic differentiation of human adipose stem cells in vitro.Stem Cell Res Ther. 2013 Feb 15;4 (1) :17.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite
Citation 01
Autophagy. 2023 Feb;19 (2) :632-643.|Eng Life Sci. 2025 Oct 13;25 (10) :e70050.|Food Hydrocoll. 2026 Mar.|Adv Mater. 2025 Jul 14:e2501306.|Adv Sci (Weinh) . 2024 Dec;11 (46) :e2400502.|Adv Sci (Weinh) . 2025 Nov 21:e08472.|Biomolecules. 2025 Nov 19;15 (11) :1623.|Cell Transplant. 2025 Jan-Dec:34:9636897251376125.

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