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L-Ascorbic acid 2-phosphate (magnesium hydrate)

CAT: 0804-HY-103701B-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-103701B-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
L-ascorbic acid 2-phosphate (2-Phospho-L-ascorbic acid) magnesium hydrate is a long-acting vitamin C derivative that can stimulate collagen formation and expression. L-ascorbic acid 2-phosphate magnesium hydrate can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs) . L-ascorbic acid 2-phosphate magnesium hydrate increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation[1][2][3].
CAS Number
1713265-25-8
Product Name Alternative
2-Phospho-L-ascorbic acid (magnesium hydrate) ; LAA2P (magnesium hydrate)
UNSPSC
12352200
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite; Phosphatase; Reactive Oxygen Species (ROS)
Type
Biochemical Assay Reagents
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/l-ascorbic-acid-2-phosphate-magnesium-hydrate.html
Purity
99.63
Solubility
H2O : 5 mg/mL (ultrasonic)
Smiles
O=P(O)(O)OC1=C([C@@](OC1=O)([H])[C@@H](O)CO)O.[Mg].O.[x].[3/2]
Molecular Formula
C6H9O9P.xH2O.3/2Mg
Precautions
H302, H315, H319, H335
References & Citations
[1]Shima N, et al. Increased proliferation and replicative lifespan of isolated human corneal endothelial cells with L-ascorbic acid 2-phosphate.Invest Ophthalmol Vis Sci. 2011 Nov 7;52 (12) :8711-7.|[2]Kurata S, et al. Epidermal growth factor inhibits transcription of type I collagen genes and production of type I collagen in cultured human skin fibroblasts in the presence and absence of L-ascorbic acid 2-phosphate, a long-acting vitamin C derivative.J Biol Chem. 1991 May 25;266 (15) :9997-10003.|[3]Kyllönen L, et al. Effects of different serum conditions on osteogenic differentiation of human adipose stem cells in vitro.Stem Cell Res Ther. 2013 Feb 15;4 (1) :17.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported

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