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L-Ascorbic acid 2-phosphate (magnesium)

CAT: 0804-HY-103701A-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-103701A-01Size:100 mg
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Description
L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) is a long-acting vitamin C derivative that can stimulate collagen formation and expression[1]. L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs) . L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation[2][3].
CAS Number
113170-55-1
Product Name Alternative
2-Phospho-L-ascorbic acid (magnesium) ; LAA2P (magnesium)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite; Phosphatase; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/l-ascorbic-acid-2-phosphate-magnesium.html
Purity
99.97
Solubility
H2O : 25 mg/mL (ultrasonic)
Smiles
OC([C@H](O1)[C@H](C[O-])O)=C(OP([O-])([O-])=O)C1=O.[1.5].[Mg+2]
Molecular Formula
C6H9O9P.3/2Mg
Molecular Weight
292.56
Precautions
H302, H315, H319, H335
References & Citations
[1]Shima N, et al. Increased proliferation and replicative lifespan of isolated human corneal endothelial cells with L-ascorbic acid 2-phosphate.Invest Ophthalmol Vis Sci. 2011 Nov 7;52 (12) :8711-7.|[2]Kurata S, et al. Epidermal growth factor inhibits transcription of type I collagen genes and production of type I collagen in cultured human skin fibroblasts in the presence and absence of L-ascorbic acid 2-phosphate, a long-acting vitamin C derivative.J Biol Chem. 1991 May 25;266 (15) :9997-10003.|[3]Kyllönen L, et al. Effects of different serum conditions on osteogenic differentiation of human adipose stem cells in vitro.Stem Cell Res Ther. 2013 Feb 15;4 (1) :17.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite

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