Apoptosis inducer 40

• Description :

  Apoptosis inducer 40 is an apoptosis inducer. Apoptosis inducer 40 exhibits potent cytotoxic effects against jurkat and NB4 cells with IC50 values of 4.5 μM and 3.6μM. Apoptosis inducer 40 induces apoptosis and arrests cell cycle. Apoptosis inducer 40 can be used for the research of cancer, such as acute myeloid leukemia (AML) [1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302-H315-H319-H335

• Target :

  Apoptosis

• Related Pathways :

  Apoptosis

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Smiles :

  O=C1NC(C2=CC=CC(Cl)=C2Cl)=NC3=CC=CC=C13

• Molecular Formula :

  C14H8Cl2N2O

• Molecular Weight :

  291.13

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations :

  [1]Antoniolli G, et al. Synthesis and Evaluation of 2‑Substituted Quinazolin-4 (3H) ‑ones as Potential Antileukemic Agents. ACS Omega. 2025 Aug 1;10 (31) :34882-34894.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [83800-90-2]