VF-149

CAT: 0804-HY-W675573Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-W675573Size:1 Each
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AVAILABILITY: InStock
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Description
VF-149 is a Ribonucleotide reductase inhibitor. VF-149 significantly inhibits Plasmodium falciparum growth with an IC50 of 6.4 μM. VF-149 has antimalarial and antitumor activities. VF-149 can be used for malarial infections and cancers research[1].
CAS Number
[16053-97-7]
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
DNA/RNA Synthesis; Parasite
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection
Smiles
O=C(C1=C(O)C(O)=CC=C1)NO
Molecular Formula
C7H7NO4
Molecular Weight
169.13
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]Holland KP, et al. Antimalarial activities of polyhydroxyphenyl and hydroxamic acid derivatives. Antimicrob Agents Chemother. 1998 Sep;42 (9) :2456-8.|[2]Elford HL, et al. New ribonucleotide reductase inhibitors with antineoplastic activity. Cancer Res. 1979 Mar;39 (3) :844-51.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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