AAL-149

• Description :

  AAL-149 is a FTY720 (HY-12005) analog and TRPM7 inhibitor (IC50 = 1.081 μM) with multimodal anti-inflammatory effects and without targeting S1P receptors. AAL-149 can be utilized in anti-inflammatory research[1].

• UNSPSC :

  12352005

• Target :

  TRP Channel

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Field of Research :

  Inflammation/Immunology

• Smiles :

  N[C@@](CO)(C)CCC1=CC=C(OCCCCCCC)C=C1

• Molecular Formula :

  C18H31NO2

• Molecular Weight :

  293.44

• References & Citations :

  [1]Busey GW, et al. Analogs of FTY720 inhibit TRPM7 but not S1PRs and exert multimodal anti-inflammatory effects. J Gen Physiol. 2024 Jan 1;156 (1) :e202313419.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  TRPM8

• CAS Number :

  [177258-60-5]