VF-57a

• Description :

  VF-57a (Compound 23) is an Influenza A virus (IAV) fusion inhibitor. VF-57 has potent antiviral activities against authentic A/H1N1 virus with EC50s of 0.92 and 0.31 μM for the A/H1N1 PR8 and A/H1N1 Virg09 strains, respectively. VF-57 significantly inhibits HA-mediated cell entry of A/H1N1- and A/H5N1-pseudoviruses, prevents the HA refolding at pH 5.2. VF-57a can be used for IAV infections research[1].

• UNSPSC :

  12352005

• Target :

  Influenza Virus

• Related Pathways :

  Anti-infection

• Field of Research :

  Infection

• Smiles :

  O=C(NCC1=C(C)SC(C)=C1)C2=CC(C(F)(F)F)=CC(Cl)=C2

• Molecular Formula :

  C15H13ClF3NOS

• Molecular Weight :

  347.78

• References & Citations :

  [1]Rimaux S, et al. N-[ (Thiophen-3-yl) methyl] benzamides as Influenza Virus Fusion Inhibitors Acting on H1 and H5 Hemagglutinins[J]. bioRxiv, 2025: 2025.07. 28.667118.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported