Antitumor agent-202

• Description :

  Antitumor agent-202 is a stabilizer of the p53 Y220C mutant. It exhibits a selective inhibitory effect on the proliferation of tumor cells carrying the p53 Y220C mutation and can be applied to the research of cancers associated with the p53 Y220C mutation[1].

• UNSPSC :

  12352005

• Target :

  MDM-2/p53

• Related Pathways :

  Apoptosis

• Field of Research :

  Cancer

• Smiles :

  C1=CC=C(C=C1)C(=O)/C=C/C2=CNC3=CC=CC=C23

• Molecular Formula :

  C17H13NO

• Molecular Weight :

  247.29

• References & Citations :

  [1]Li L, et al. Design, synthesis, and activity evaluation of indole derivatives as potential stabilizers for p53 Y220C. Bioorg Med Chem Lett. 2025 Jun 1;121:130161.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound2

• Clinical Information :

  No Development Reported

• CAS Number :

  [38470-63-2]