Apoptosis inducer 54

• Description :

  Apoptosis inducer 54 is an apoptosis inducer that interacts with topoisomerase II-DNA. Apoptosis inducer 54 induces cell cycle arrest at the S phase in cancer cells. Apoptosis inducer 54 significantly induces early and late apoptosis in A549 cells. Topoisomerase I-IN-20 can be used for the research of lung cancer and colon cancer[1].

• UNSPSC :

  12352005

• Target :

  Apoptosis; Topoisomerase

• Related Pathways :

  Apoptosis; Cell Cycle/DNA Damage

• Field of Research :

  Cancer

• Smiles :

  O=C(NC1=CC=C(OC)C=C1OC)CN2N=NC(CN3C(C4=CC(OC)=C(OC)C(OC)=C4)=NC5=CC=CC=C35)=C2

• Molecular Formula :

  C29H30N6O6

• Molecular Weight :

  558.59

• References & Citations :

  [1]Shokouhi Asl AS, et al. Synthesis, biological evaluation, and docking analysis of novel benzimidazole-triazole hybrids as potential anticancer agents. RSC Adv. 2025;15 (44) :37447-37460. Published 2025 Oct 8.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported