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Apoptosis inducer 46

CAT: 0804-HY-178132Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-178132Size:1 Each
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Description
Apoptosis inducer 46 is an apoptosis inducer. Apoptosis inducer 46 exhibits potent and selective growth inhibitory effects on metastatic triple-negative breast cancer (TNBC) cells. Apoptosis inducer 46 induces G2/M phase cell cycle arrest and apoptotic cell death in MDA-MB-231 cells, and blocks NF-κB nuclear translocation. Apoptosis inducer 46 can be used for the study of TNBC[1].
CAS Number
3085356-41-5
UNSPSC
12352005
Target
Apoptosis; NF-κB
Related Pathways
Apoptosis; NF-κB
Field of Research
Cancer
Smiles
OC1=C(C=C(C=C1)/C=C2CN(C3CC3)C/C(C\2=O)=C\C4=CC=C(C=C4)C)OC
Molecular Formula
C24H25NO3
Molecular Weight
375.46
References & Citations
[1]Khor PY, et al. Discovery of New Non-Symmetrical Heterocyclic Pentanoid Derivatives Targeting Metastatic Triple-Negative Breast Cancer. Bioorg Med Chem Lett. 2025 Aug 1;123:130232.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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