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MG degrader 3

CAT: 0804-HY-177728Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-177728Size:1 Each
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Description
MG degrader 3 is a molecular glucose degrading agent that targets the CRBN protein. MG degrader 3 has certain anti proliferative activity in MM.1S cells (IC50 = 8.7 nM) . MG degrader 3 can be used for cancer research[1].
CAS Number
2413733-73-8
UNSPSC
12352005
Target
Molecular Glues
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C(NC1=CC=C(C)C(Cl)=C1)CCCOC2=CC=CC3=C2CN(C(CC4)C(NC4=O)=O)C3=O
Molecular Formula
C24H24ClN3O5
Molecular Weight
469.92
References & Citations
[1]Xu Y, et al. Cross-Linking Profiling of Molecular Glue Degrader-Induced E3 Ligase Interactome to Expand Target Space. Angew Chem Int Ed Engl. 2025 May 26;64 (22) :e202505053.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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