WIZ degrader 3

WIZ degrader 3

• CAS Number: 2839637-72-6
• UNSPSC Description: WIZ degrader 3 (Compound 29) is a degrader for widely interspaced zinc finger motifs (WIZ), with an AC50 of 6.4 nM. WIZ degrader 3 induces the expression of fetal hemoglobin (HbF), with an EC50 of 45 nM. WIZ degrader 3 can be used for the research of blood disorders, such as sickle cell disease and β- thalassemia[1].
• Target Antigen: Histone Acetyltransferase
• Type: Reference compound
• Related Pathways: Epigenetics
• Applications: Neuroscience-Neuromodulation
• Field of Research: Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/wiz-degrader-3.html
• Smiles: O=C(NC(CC1)=O)N1C2=NOC3=CC=C(C=C23)CN4C[C@@H](N(CC4)C)C
• Molecular Weight: 357.41
• References & Citations: [1]BECKWITH IREJ, et al. Benzisoxazole derivatives and uses thereof. WO2022195355A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported