RORγ agonist 2

• Description :

  RORγ agonist 2 (Compound 34) is a selective RORγ agonist with an EC50 of 0.03 μM for hRORγ. RORγ agonist 2 significantly inhibits tumors growth in syngeneic MC38 tumor mice model[1].

• UNSPSC :

  12352005

• Target :

  ROR

• Related Pathways :

  Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

• Field of Research :

  Cancer

• Smiles :

  CCS(=O)(C1CCN(C(C)=O)C(C(NC2=CC(F)=C(C(C(F)(F)F)=C2)OC3=CC(C4CC4)=NC(C5CC5)=C3)=O)C1)=O

• Molecular Formula :

  C28H31F4N3O5S

• Molecular Weight :

  597.62

• References & Citations :

  [1]Fukuda S, et al. A Concise and Modular Approach to Generate Novel RORγ Agonists. J Med Chem. 2025 Jul 18.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  RORα; RORγ