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RORγt agonist 3

CAT: 0931-T64017-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T64017-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2664106-24-3
Target
Others, ROR
Related Pathways
Others, Metabolism
Bioactivity
RORγt agonist 3 is a potent agonist of RORγt that induces Th17 cell differentiation, increases levels of pro-inflammatory cytokines, and enhances lymphocyte cytotoxicity. Moreover, [it] blocks the production of regulatory T cells and suppresses the immune response.
Smiles
N(CC1CC1)(C2=CC(=CC(=C2)C3CC3)C4CC4)C5=CC=C(C(N[C@@H](CC#N)C6=CC=C(S(CC)(=O)=O)C=C6)=O)C=C5
Molecular Formula
C34H37N3O3S
Molecular Weight
567.74
Shipping Conditions
Ice Packs
Storage Temperature
-20°C