RORγt agonist 3

• UNSPSC Description:

  RORγt agonist 3 is a potent agonist of RORγt. RORγt agonist 3 promotes the differentiation of Th17 cells and enhances the levels of pro-inflammatory cytokines, thereby increasing the cytotoxicity of lymphocytes. RORγt agonist 3 inhibits the production of regulatory T cells, which suppresses the immune response (extracted from patent WO2021136326A1, compound 23)[1].

• Target Antigen:

  ROR

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/rorγt-agonist-3.html

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  N#CC[C@@H](C1=CC=C(C=C1)S(CC)(=O)=O)NC(C(C=C2)=CC=C2N(C3=CC(C4CC4)=CC(C5CC5)=C3)CC6CC6)=O

• Molecular Weight:

  567.74

• References & Citations:

  [1]Liu Bin, et al. Aromatic amides and their use in pharmaceuticals. Patent WO2021136326A1.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2664106-24-3