RORγt inverse agonist 23

• UNSPSC Description:

  RORγt inverse agonist 23 is a potent, selective, and orally available novel retinoic acid receptor-related orphan receptor γt inverse agonist.

• Target Antigen:

  ROR

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/rorγt-inverse-agonist-23.html

• Solubility:

  DMSO : ≥ 100 mg/mL

• Smiles:

  OC1C2=C(C=CC(S(N(C3=CC=C(CC)C=C3)C4CCC4)(=O)=O)=C2)OC(C5CCOCC5)C1

• Molecular Weight:

  471.61

• References & Citations:

  [1]Chen L, et al. Discovery of Chromane-6-Sulfonamide Derivative as a Potent, Selective, and Orally Available Novel Retinoic Acid Receptor-Related Orphan Receptor γt Inverse Agonist. J Med Chem. 2021 Nov 11;64(21):16106-16131.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2230779-18-5