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ROR agonist-1

CAT: 0931-T12750-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T12750-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2361528-74-5
Target
Others|||ROR
Related Pathways
Metabolism|||Others
Bioactivity
ROR agonist-1 is a potent and orally bioavailable inverse agonist of the retinoic acid receptor-related orphan receptor C2 (RORC2), demonstrating inhibition of IL-17A production from human primary TH17 cells with a pIC50 of 7.5.
Smiles
C(C(F)(F)F)(C(F)(F)F)(O)C1=CC=C(NC([C@H](NC(C)=O)C2=CC=C(S(CC)(=O)=O)C=C2)=O)C=C1
Molecular Formula
C21H20F6N2O5S
Molecular Weight
526.45
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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