ROR agonist-1

• Target :

  Others|||ROR

• Related Pathways :

  Metabolism|||Others

• Bioactivity :

  ROR agonist-1 is a potent and orally bioavailable inverse agonist of the retinoic acid receptor-related orphan receptor C2 (RORC2), demonstrating inhibition of IL-17A production from human primary TH17 cells with a pIC50 of 7.5.

• Smiles :

  C(C(F)(F)F)(C(F)(F)F)(O)C1=CC=C(NC([C@H](NC(C)=O)C2=CC=C(S(CC)(=O)=O)C=C2)=O)C=C1

• Molecular Formula :

  C21H20F6N2O5S

• Molecular Weight :

  526.45

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2361528-74-5