Cs-2d

• Description :

  Cs-2d is a selective ceramide synthases Cer1 inhibitor. Cs-2d has potent inhibitory activity toward C. neoformans Cer1, while maintaining a low off-target effect on human hCerS1. Cs-2d has potent antifungal activity with the significant growth inhibition. Cs-2d can be used for invasive fungal infections research[1].

• UNSPSC :

  12352005

• Target :

  Acyltransferase; Fungal

• Related Pathways :

  Anti-infection; Metabolic Enzyme/Protease

• Field of Research :

  Infection

• Smiles :

  NCCCCCN1C(C2=C(C)C=C(OCO3)C3=C2)=C(C4=CC=CC=C4)N=C1.Cl.Cl

• Molecular Formula :

  C22H27Cl2N3O2

• Molecular Weight :

  436.37

• References & Citations :

  [1]Dasilva D, et al. Targeting ceramide synthases for the development of new antifungals. Structure. 2025 Jun 12:S0969-2126 (25) 00213-8.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2928129-57-9]