CS-526

CAT: 0804-HY-100413Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-100413Size:1 Each
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Description
CS-526 is a potent, selective, reversible and orally active acid pump antagonist. CS-526 inhibits H+, K+-ATPase activity. CS-526 inhibits gastric acid secretion and prevents esophageal lesions. CS-526 has the potential for the research of gastroesophageal reflux disease[1].
CAS Number
[313272-12-7]
UNSPSC
12352005
Target
Proton Pump
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cs-526.html
Solubility
10 mM in DMSO
Smiles
C[C@@H]1[C@@H](CN2C(C)=C(C)C3=C2C(OCC4=CC=C(F)C=C4)=NN=C3)C1
Molecular Formula
C20H22FN3O
Molecular Weight
339.41
References & Citations
[1]Ito K, et al. Pharmacological profile of novel acid pump antagonist 7- (4-fluorobenzyloxy) -2,3-dimethyl-1-{[ (1S,2S) -2-methyl cyclopropyl]methyl}-1H-pyrrolo[2,3-d]pyridazine (CS-526) . J Pharmacol Exp Ther. 2007 Oct;323 (1) :308-17.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1

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