CS-526

• Description :

  CS-526 is a potent, selective, reversible and orally active acid pump antagonist. CS-526 inhibits H+, K+-ATPase activity. CS-526 inhibits gastric acid secretion and prevents esophageal lesions. CS-526 has the potential for the research of gastroesophageal reflux disease[1].

• UNSPSC :

  12352005

• Target :

  Proton Pump

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/cs-526.html

• Solubility :

  10 mM in DMSO

• Smiles :

  C[C@@H]1[C@@H](CN2C(C)=C(C)C3=C2C(OCC4=CC=C(F)C=C4)=NN=C3)C1

• Molecular Formula :

  C20H22FN3O

• Molecular Weight :

  339.41

• References & Citations :

  [1]Ito K, et al. Pharmacological profile of novel acid pump antagonist 7- (4-fluorobenzyloxy) -2,3-dimethyl-1-{[ (1S,2S) -2-methyl cyclopropyl]methyl}-1H-pyrrolo[2,3-d]pyridazine (CS-526) . J Pharmacol Exp Ther. 2007 Oct;323 (1) :308-17.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 1

• CAS Number :

  [313272-12-7]