CS-0777

• Description :

  CS-0777 is a selective, orally active sphingosine 1-phosphate receptor-1 modulator. CS-0777 can be used in the research of autoimmune diseases[1][2].

• UNSPSC :

  12352005

• Target :

  LPL Receptor

• Related Pathways :

  GPCR/G Protein

• Field of Research :

  Inflammation/Immunology

• Smiles :

  CN1C(CC[C@@](CO)(C)N)=CC=C1C(CCCC2=CC=C(C)C=C2)=O

• Molecular Formula :

  C21H30N2O2

• Molecular Weight :

  342.48

• References & Citations :

  [1]Inaba SI, Yamaguchi-Goto M, Tanaka-Takanaka K, Yonesu K, Sakurai H, Kubota K, Izumi T. Enzymatic kinetics regarding reversible metabolism of CS-0777, a sphingosine 1-phosphate receptor modulator, via phosphorylation and dephosphorylation in humans. Xenobiotica. 2018 Mar;48 (3) :258-268. |[2]Moberly JB, et al. Pharmacological effects of CS-0777, a selective sphingosine 1-phosphate receptor-1 modulator: results from a 12-week, open-label pilot study in multiple sclerosis patients. J Neuroimmunol. 2012 May 15;246 (1-2) :100-7.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 1

• Isoform :

  S1PR1

• CAS Number :

  [827344-05-8]