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PDE4 ligand 2

CAT: 0804-HY-174410Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-174410Size:1 Each
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Description
PDE4 ligand 2 is a CRBN E3 ligase ligand. PDE4 ligand 2 can be used to synthesize PROTAC such as PDE4 degrader-1. PDE4 ligand 2 can be studied in research for autoimmune and anti-inflammatory diseases[1].
UNSPSC
12352100
Target
Ligands for Target Protein for PROTAC
Related Pathways
PROTAC
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
OC(C1=CSC(C2=CC=C(C(OCC3CC3)=C2)OC(F)F)=N1)=O
Molecular Formula
C15H13F2NO4S
Molecular Weight
341.33
References & Citations
[1]Liu, Y., et al., (2025) . Discovery of novel PDE4 degraders with in vivo anti-inflammatory efficacy. Bioorganic chemistry, 163, 108675. Advance online publication.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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