PDE4 ligand 2

• Description :

  PDE4 ligand 2 is a CRBN E3 ligase ligand. PDE4 ligand 2 can be used to synthesize PROTAC such as PDE4 degrader-1 (HY-174405) . PDE4 ligand 2 can be studied in research for autoimmune and anti-inflammatory diseases[1].

• UNSPSC :

  12352100

• Target :

  Ligands for Target Protein for PROTAC

• Related Pathways :

  PROTAC

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Smiles :

  OC(C1=CSC(C2=CC=C(C(OCC3CC3)=C2)OC(F)F)=N1)=O

• Molecular Formula :

  C15H13F2NO4S

• Molecular Weight :

  341.33

• References & Citations :

  [1]Liu, Y., et al., (2025) . Discovery of novel PDE4 degraders with in vivo anti-inflammatory efficacy. Bioorganic chemistry, 163, 108675. Advance online publication.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported