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STAT3-IN-43

CAT: 0804-HY-174386Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-174386Size:1 Each
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Description
STAT3-IN-43 (Compound K2) is a covalent inhibitor targeting the allosteric site at the junction of the STAT3 coiled-coil domain and DNA-binding domain, with an IC50 of 40.7 μM. STAT3-IN-43 can be used in cancer research[1].
CAS Number
2761657-21-8
UNSPSC
12352005
Target
STAT
Related Pathways
JAK/STAT Signaling; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
BrC1=CC(CNC(C2CCCN(C(C=C)=O)C2)=O)=CC3=C1OCO3
Molecular Formula
C17H19BrN2O4
Molecular Weight
395.25
References & Citations
[1]Szalai TV, et al. Allosteric Covalent Inhibitors of the STAT3 Transcription Factor from Virtual Screening. ACS Med Chem Lett. 2025 May 6;16 (6) :991-997.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
STAT3

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335744-01Stat3

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