Antitumor agent-203

• Description :

  Antitumor agent-203 (compound 26) is a derivative of Exatecan (DX-8951) (HY-13631) and can be used to prepare antibody-drug conjugates (ADCs), as the ADC Cytotoxin[1].

• UNSPSC :

  12352005

• Target :

  ADC Payload; Topoisomerase

• Related Pathways :

  Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Purity :

  99.07

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  C[C@@H](O)C(N[C@@H]1C2=C3C(C(N4C3)=CC([C@](O)(C(OC5)=O)CC)=C5C4=O)=NC6=CC(F)=C(C)C(CC1)=C62)=O

• Molecular Formula :

  C27H26FN3O6

• Molecular Weight :

  507.51

• References & Citations :

  [1]Zhu Yi, et al. Preparation of exatecan derivatives and exatecan antibody conjugates useful for the treatment of cancer. China, CN111689980 A. 2020-09-22.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, stored under nitrogen)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2577204-44-3]