PPARγ-IN-5

• Description:

  PPARγ-IN-5 (Compound A3) is the inhibitor for PPARγ. PPARγ-IN-5 inhibits lipid accumulation in hepatocytes without significant cytotoxicity in HepG2 cell (400 µM) . PPARγ-IN-5 can be used in research of non-alcoholic fatty liver disease[1].

• UNSPSC:

  12352005

• Target:

  PPAR

• Related Pathways:

  Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

• Field of Research:

  Inflammation/Immunology

• Smiles:

  O=C(O)/C=C/C1=CC=C(OCCOC(C(C)(OC2=CC=C(Cl)C=C2)C)=O)C(OC)=C1

• Molecular Formula:

  C22H23ClO7

• Molecular Weight:

  434.87

• References & Citations:

  [1]Liu YY, et al., Design, synthesis, and inhibition of novel ferulic acid derivatives on free fatty acid induced cellular lipid accumulation. J Asian Nat Prod Res. 2025 Feb 23:1-16.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  PPARγ

• CAS Number:

  [3038323-12-2]