PPARγ-IN-5

• Description :

  PPARγ-IN-5 (Compound A3) is the inhibitor for PPARγ. PPARγ-IN-5 inhibits lipid accumulation in hepatocytes without significant cytotoxicity in HepG2 cell (400 µM) . PPARγ-IN-5 can be used in research of non-alcoholic fatty liver disease[1].

• UNSPSC :

  12352005

• Target :

  PPAR

• Related Pathways :

  Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

• Field of Research :

  Inflammation/Immunology

• Smiles :

  O=C(O)/C=C/C1=CC=C(OCCOC(C(C)(OC2=CC=C(Cl)C=C2)C)=O)C(OC)=C1

• Molecular Formula :

  C22H23ClO7

• Molecular Weight :

  434.87

• References & Citations :

  [1]Liu YY, et al., Design, synthesis, and inhibition of novel ferulic acid derivatives on free fatty acid induced cellular lipid accumulation. J Asian Nat Prod Res. 2025 Feb 23:1-16.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  PPARγ

• CAS Number :

  [3038323-12-2]