RegisterLogin

CDD-1115

CAT: 0804-HY-171248Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-171248Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
CDD-1115 is a potent, selective inhibitor of BMPR2 with IC50 of 1.8 nM, Kiapp of 6.2 nM. CDD-1115 inhibits bone morphogenetic protein (BMP) -mediated gene expression. BMP controls cellular processes across many tissue types, including the kidney, skeletal muscle, heart, and reproductive organs. BMP induces ectopic bone formation[1].
CAS Number
[3034215-86-3]
UNSPSC
12352005
Target
Anaplastic lymphoma kinase (ALK)
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Endocrinology; Cardiovascular Disease
Smiles
NC(C1=CC=CC(CNC(C2=CC=C3N=C(C4=CC5=C(C=NC=C5)C=C4)N([C@H]6C[C@@H](CC6)C(NC)=O)C3=C2)=O)=C1)=O
Molecular Formula
C32H30N6O3
Molecular Weight
546.62
References & Citations
[1]Modukuri RK, et al. Discovery of Highly Potent and BMPR2-Selective Kinase Inhibitors Using DNA-Encoded Chemical Library Screening. J Med Chem. 2023 Feb 9;66 (3) :2143-2160.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-129571-01BioE-1115
HY-103182-01PSB-1115
HY-P991645MDX-1115
HY-162565-01CDD-2807
HY-177143CDD-1498
HY-103182R-01PSB-1115 (Standard)
HY-155144-01CDD-1845
HY-162779-01CDD-3290
HY-155142CDD-1819
HY-171249CDD-1431

Alternative Products

CatalogName
T205172-01CDD-1115
463165-01PSB 1115
BUP16374-01BioE-1115
M10360-01PV-1115
T9901A-1853-01MDX-1115
A22301-10BioE-1115 10mg
A22301-50BioE-1115 50mg

Popular Products