CDD-1281

CAT: 0804-HY-171247Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-171247Size:1 Each
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CDD-1281 is a highly potent and selective BMPR2 kinase inhibitor with an IC50 of 1.2 nM. CDD-1281 can effectively inhibit BMP-mediated gene expression[1].
CAS Number
[3034215-91-0]
UNSPSC
12352005
Target
TGF-β Receptor
Related Pathways
TGF-beta/Smad
Field of Research
Others
Smiles
O=C(C1=CC=CC(CNC(C2=CC3=C(N=C(N3C4CCCC4)C5=CC6=C(C=NC=C6)C=C5)C=C2)=O)=C1)N
Molecular Formula
C30H27N5O2
Molecular Weight
489.57
References & Citations
[1]Modukuri RK, et al. Discovery of Highly Potent and BMPR2-Selective Kinase Inhibitors Using DNA-Encoded Chemical Library Screening. J Med Chem. 2023 Feb 9;66 (3) :2143-2160.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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