CDD-1733

• Description:

  CDD-1733 is a non-covalent and non-peptide potent SARS-CoV-2 Mpro inhibitor with a Ki of 12 nM. CDD-1733 also inhibits ΔP168, A173V, and ΔP168/A173V Mpro variants[1].

• UNSPSC:

  12352005

• Target:

  SARS-CoV

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/cdd-1733.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C (NC) [C@@] (C1) ([H]) C[C@]1 ([H]) N2C (C3=C (C=CC=C4) C4=CN=C3) =NC5=C2C (C (N[C@@H] (CCC) C6=CC=C (C (F) (F) F) C=C6) =O) =CC=C5

• Molecular Formula:

  C34H32F3N5O2

• Molecular Weight:

  599.65

• References & Citations:

  [1]Ravikumar Jimmidi, et al. DNA-encoded chemical libraries yield non-covalent and non-peptidic SARS-CoV-2 main protease inhibitors. Commun Chem. 2023 Aug 4;6 (1) :164.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2894104-33-5