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BioE-1115

CAT: 0804-HY-129571-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-129571-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BioE-1115 is a highly selective and potent PAS kinase (PASK) inhibitor with an IC50 of ~4 nM. BioE-1115 is also a potent casein kinase 2α inhibitor with an IC50 of ~10 μM[1].
CAS Number
1268863-35-9
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Casein Kinase; Ser/Thr Protease
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Stem Cell/Wnt
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/bioe-1115.html
Purity
98.17
Solubility
DMSO : 62.5 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C2N=C(C3=CC=C(F)C=C3)C(N(C)C(C)C)=NC2=C1)O
Molecular Formula
C19H18FN3O2
Molecular Weight
339.36
Precautions
H302, H315, H319, H335
References & Citations
[1]Wu X, et al. PAS kinase drives lipogenesis through SREBP-1 maturation. Cell Rep. 2014 Jul 10;8 (1) :242-55.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CK2

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