CDD-2807

CAT: 0804-HY-162565-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-162565-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
CDD-2807 is an inhibitor for serine/threonine kinase 33 (STK33) with IC50 of 9.2 nM. CDD-2807 exhibits no significant toxicity in mice and can cross the blood-testis barrier without accumulating in the brain. CDD-2807 induces a reversible contraceptive effect and has potential for the development of the male contraceptive[1].
CAS Number
[3086536-23-1]
UNSPSC
12352005
Target
CDK; RET; STK33
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Protein Tyrosine Kinase/RTK
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/cdd-2807.html
Purity
99.52
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(C1=CC2=C(NN=C2C#CC3=CC=CC=C3C4=CC=CC=C4)C=C1)N5CC6(CNCCC6)C5
Molecular Formula
C29H26N4O
Molecular Weight
446.54
References & Citations
[1]Ku AF, et al., Reversible male contraception by targeted inhibition of serine/threonine kinase 33. Science. 2024 May 24;384 (6698) :885-890.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CLK

Related Products

CatalogName
HY-177143CDD-1498
HY-171248CDD-1115
HY-162779-01CDD-3290
HY-155142CDD-1819
HY-155144-01CDD-1845
HY-177140CDD-1147
HY-176885CDD-2211
HY-176884CDD-2110
HY-171249CDD-1431
HY-179510CDD-1274

Alternative Products

CatalogName
T210217-01CDD-2807
M13602-01GSK-2807
MBS5812283GSK-2807 free base
T79345-01CDD-1733
T79346-01CDD-1845
T89314-01CDD-3290
T88619-01CDD-1653
T205131-01CDD-1281
MBS5821006CDD-1819
T206617-01CDD-2789

Popular Products