CDD-1115

• Target :

  ALK

• Related Pathways :

  Tyrosine Kinase/Adaptors|||Angiogenesis

• Bioactivity :

  CDD-1115 is a potent and selective BMPR2 inhibitor, with an IC50 of 1.8 nM and a Kiapp of 6.2 nM. It effectively suppresses gene expression mediated by bone morphogenetic proteins (BMPs) . BMPs regulate cellular processes in various tissue types, such as the kidneys, skeletal muscle, heart, and reproductive organs, and can induce ectopic bone formation.

• Smiles :

  C(NCC1=CC(C(N)=O)=CC=C1)(=O)C=2C=C3N(C(=NC3=CC2)C4=CC5=C(C=C4)C=NC=C5)[C@H]6C[C@H](C(NC)=O)CC6

• Molecular Formula :

  C32H30N6O3

• Molecular Weight :

  546.619

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  3034215-86-3