BD-Oligo

• Description :

  BD-Oligo is an oligomer-specific fluorescent chemical probe. BD-Oligo preferentially identifies Aβ oligomer assemblies over monomers or fibrils by using diversity-directed fluorescent library (DOFL) screening and computational techniques. BD-Oligo exhibits dynamic oligomer monitoring capabilities during Aβ peptide fibril formation as Aβ is induced to form oligomers and ultimately fibrils over time. BD-Oligo also exhibits blood-brain barrier permeability with the ability to stain Aβ oligomers in vivo[1].

• UNSPSC :

  12352005

• Target :

  Fluorescent Dye

• Related Pathways :

  Others

• Applications :

  Neuroscience-Neurodegeneration

• Field of Research :

  Neurological Disease

• Purity :

  98.18

• Smiles :

  OC(C(OCC)=CC=C1)=C1/C=C/C2=[N]3C(C(C)=C2)=CC4=CC=C(CCC(OCC(Cl)(Cl)Cl)=O)[N-]4[B+3]3([F-])[F-]

• Molecular Formula :

  C25H24BCl3F2N2O4

• Molecular Weight :

  571.64

• References & Citations :

  [1]Teoh CL, et al. Chemical Fluorescent Probe for Detection of Aβ Oligomers. J Am Chem Soc. 2015 Oct 28;137 (42) :13503-9.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, sealed storage, away from moisture and light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1357578-02-9]